Unlocking
Cell Therapies
for Cancer

AI-Powered Discovery of T-Cell-Receptor-Based Cancer Immunotherapies

Data

In-house generation of massive TCR-target interaction datasets using cutting-edge
high-throughput screening techniques

Model

In silico predictions of TCR-target interactions through deep learning models trained on our proprietary datasets

Discover

Discovery of novel tumour targets shared across patients and safe and effective target-specific TCRs

Our team

Federico Paoletti

CEO and CO-FOUNDER

Federico is a computational biologist with deep expertise in mathematical modelling and molecular biophysics. He holds a PhD in Molecular and Computational Oncology from the University of Oxford and has previously worked at the World Health Organization assessing cancer prevention strategies.

Andrea Mambrini

CTO and CO-FOUNDER

Andrea is an experienced Machine Learning Scientist. He holds a PhD in Bio-Inspired Computation from the University of Birmingham and has several years of hands-on experience building cutting-edge AI. He has previously led the ML team at Portent.io (acquired by Yougov) and has worked at the European Space Agency, Honda Research Institute and Vodafone.

Amanda Woon

HEAD of CELL BIOLOGy

Amanda is an experienced cell biologist. She holds a  PhD in Biochemistry and Molecular Biology from Monash University (Australia) and she has previously developed TCR bi-specifics for the treatment of cancers and infectious diseases at Immunocore, a top TCR company.  

Bowen Tian

Head of Protein Science

Bowen is an expert in biochemistry and protein purification in the immuno-oncology space. He holds a  PhD in Drug Discovery from University College London and has gained experience in TCR and CAR discovery at Autolus and Immunocore, two top cell therapy companies. 

Ricardo Fernandes

Scientific Advisor

Ricardo is a world expert in  wet-lab methods for high-throughput screening of TCR-target pairs. He is a Principal Investigator at the University of Oxford and he has published in high-profile journals such as Nature Immunology, Cell and PNAS.

Alasdair Thong

Commercial ADVISOR

Alasdair has extensive experience negotiating and managing AI-driven co-development partnerships in the biopharmaceutical industry. He is a Founding Partner at Selvedge Venture and former director of deep-tech venture investments at Leaps by Bayer.

Featured

Partners

Email:

info@exogene.co.uk

Reg. Number:

12293407

Address:

Oxford BioEscalator, Innovation Building, Old Road Campus, Roosevelt Drive, Oxford, OX3 7FZ, United Kingdom