AI-Powered Discovery of T-Cell-Receptor-Based Cancer Immunotherapies

Data
In-house generation of massive TCR-target interaction datasets using cutting-edge
high-throughput screening techniques

Model
In silico predictions of TCR-target interactions through deep learning models trained on our proprietary datasets

Discover
Discovery of novel tumour targets shared across patients and safe and effective target-specific TCRs
Our Team

Federico Paoletti
CEO & Co-Founder

Andrea Mambrini
CTO & Co-Founder

Amanda is an experienced immunologist with expertise in protein science and cell biology. She holds a PhD in Biochemistry and Molecular Biology from Monash University (Australia) and she has previously developed TCR bi-specifics for the treatment of cancers and infectious diseases at Immunocore, a top TCR company.
Amanda Woon
Head of R&D

Ryan is an experienced machine learning scientist with a PhD in Chemistry from Cornell University. He joined Exogene from the machine learning group at Bayer and his recent work there was published at ICML. He previously worked at Intel, and in his spare time he participates in machine learning competitions.
Ryan Henderson
Machine Learning Scientist

Angelos has worked at the interface of science and business. He was previously a Project Manager at Multiomic Health, a precision medicine company developing assets for metabolic syndrome. He also evaluates deep-tech startups at Selvedge Venture, and previously did research in cancer biology and autoimmunity.
Angelos Spiliopoulos
Chief of Staff

Amy Hall
Lab Operations Manager

Hendry is a biomedical scientist with research experience in cancer and developmental biology. He previously worked for CyanoCapture, an award-winning decarbonisation start-up where he applied cellular and molecular techniques to novel organisms.
Hendry Lo
Research Assistant

Ricardo Fernandes
Scientific Advisor

Alasdair Thong
Commercial Advisor
Federico Paoletti
CEO & Co-Founder
Federico is a computational biologist with deep expertise in mathematical modelling and molecular biophysics. He holds a PhD in Molecular and Computational Oncology from the University of Oxford and has previously worked at the World Health Organization assessing cancer prevention strategies.
Andrea Mambrini
CTO & Co-Founder
Andrea is an experienced machine learning scientist. He holds a PhD in Bio-Inspired Computation and has several years of experience building AI. He previously led the ML team at Portent.io (acquired by Yougov) and has worked at the European Space Agency, Honda Research Institute and Vodafone.
Amanda Woon
Head of R&D
Amanda is an experienced immunologist with expertise in protein science and cell biology. She holds a PhD in Biochemistry and Molecular Biology from Monash University (Australia) and she has previously developed TCR bi-specifics for the treatment of cancers and infectious diseases at Immunocore, a top TCR company.
Ryan Henderson
Machine Learning Scientist
Ryan is an experienced machine learning scientist with a PhD in Chemistry from Cornell University. He joined Exogene from the machine learning group at Bayer and his recent work there was published at ICML. He previously worked at Intel, and in his spare time he participates in machine learning competitions.
Angelos Spiliopoulos
Chief of Staff
Angelos has worked at the interface of science and business. He was previously a Project Manager at Multiomic Health, a precision medicine company developing assets for metabolic syndrome. He also evaluates deep-tech startups at Selvedge Venture, and previously did research in cancer biology and autoimmunity.
Amy Hall
Lab Operations Manager
Amy has 10+ years of experience working as a senior laboratory technician. She brings extensive logistic experience in running and scaling wet-labs, together with hands-on lab skills. She worked as Lab Operations Specialist at Exscientia and as Senior Lab Technician at Sharp Life Science.
Hendry Lo
Research Assistant
Hendry is a biomedical scientist with research experience in cancer and developmental biology. He previously worked for CyanoCapture, an award-winning decarbonisation start-up where he applied cellular and molecular techniques to novel organisms.


Email:
info@exogene.co.uk
Reg. Number:
12293407
Address:
Oxford BioEscalator, Innovation Building, Old Road Campus, Roosevelt Drive, Oxford, OX3 7FZ, United Kingdom